Toxicidad cardiaca y UFT

Terapia de resincronización cardiaca. Indicaciones y contraindicaciones

Progress in medical therapy wouldn’t be possible without the contribution of the scientific community. Several randomized controlled trials have led to our current guidelines. Specifically, COMPANION and CARE-HF trials involved a turning point for cardiac resynchronization therapy, which became well recognized for the treatment of heart failure patients with QRS 120 ms, ejection fraction 35%, a...

Clonación, expresión y purificación de la troponina I cardiaca humana y su fragmento aminoterminal en Escherichia coli

Cloning, Expression and Purification of Human Cardiac Troponin I and Its Specific Amino-terminal Fragment in Escherichia coli. The human cardiac troponin I (TnIc) is nowadays the most cardiospecific diagnostic marker for acute myocardial infarction. The cardiac isoform of troponin I contains 32 additional amino acids on the Nterminus, which confer cardiac specificity. This paper describes the i...

Unification of Fusion Theories (UFT)

Since no fusion theory neither rule fully satisfy all needed applications, the author proposes a Unification of Fusion Theories and a combination of fusion rules in solving problems/applications. For each particular application, one selects the most appropriate model, rule(s), and algorithm of implementation. We are working in the unification of the fusion theories and rules, which looks like a...

UFT: mechanism of drug action.

The mechanism of action of fluorouracil (5-FU) and the oral fluoropyrimidines and the importance of biochemical modulation and inhibition of dihydropyrimidine dehydrogenase for oral application of the prodrugs of 5-FU are discussed. The regulation of thymidylate synthase, as well as its roles as a target for antineoplastic activity and in drug resistance, are also mentioned. The more downstream...

Assessment report on Leonurus cardiaca L . , herba